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Topic:

Aneurysmal Bone Cyst

Issue:

​

Category:

Oncology

Title:

Use of Surgical Adjuvants Does Not Decrease Recurrence of Aneurysmal Bone Cysts in Surgical Intervention With Pediatric Patients

Author:

Gettleman, Brandon S. BS; Padilla, Abigail N. BS; Kumar, Shourya BS; Wren, Tishya A.L. PhD; Miller, Joseph MD; Pawel, Bruce R. MD; Tolo, Vernon T. MD; Christ, Alexander B. MD

Journal:

Journal of Pediatric Orthopaedics

Date:

January 2024

Reference:

44(1): p e79-e83, DOI: 10.1097/BPO.0000000000002536

Level Of Evidence:

III

# of Patients:

129

Study Type:

Retrospective review

Location:

Tertiary pediatric hospital

Summary:

The study investigates whether the use of surgical adjuvants (e.g., high-speed burr, coagulation, liquid nitrogen, hydrogen peroxide) influences the recurrence of aneurysmal bone cysts (ABCs) in pediatric patients. The study also assesses recurrence based on age, sex, and physeal contact.

Methods:

The study involved a retrospective review from 2004 to 2020, analyzing patients who underwent surgery for histologically confirmed ABCs with at least 6 months follow-up. Data on demographics, lesion location, treatment method, and recurrence rates were collected. Statistical analyses were performed using STATA.

Exclusions:

Patients treated for recurrent tumors or with incomplete records were excluded.

Results:

70.5% of patients received surgical adjuvants, with no significant difference in recurrence between those who did and those who did not (25.3% vs. 23.7%, P = 1.000). Physeal contact was not significantly associated with recurrence (P = 0.146). Patients younger than 6 years old had a higher recurrence rate than those 6 years and older (66.7% vs. 21.7%, P = 0.007).

Conclusions:

The study found no evidence that surgical adjuvants reduce recurrence rates for ABCs. Younger patients (under 6 years old) had a higher recurrence rate, but no significant association was found with physeal contact or sex.

Relevance:

Limitations:

Perspective:

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